Cotton swabs (American English) or cotton buds (British English) or ear buds (South-African English) consist of a small wad of cotton wrapped around one or both ends of a short rod, usually made of either wood, rolled paper, or plastic. They are commonly used in a variety of applications including first aid, cosmetics application, cleaning, and arts and crafts. The cotton swab was invented in the 1920s by Leo Gerstenzang after he attached wads of cotton to toothpicks. His product, which he named "Baby Gays", went on to become the most widely sold brand name, "Q-tips", with the Q standing for "quality". The term "Q-tips" is often used as a genericized trademark for cotton swabs in the USA. Although doctors have said for years that usage of the cotton swab for ear cleaning is not safe, that use remains the most common.

The traditional sheep wool swab has a single tip on a wooden handle, and these are still often used, especially in medical settings. They are usually relatively long, about six inches (15 cm). These often are packaged sterile, one or two to a paper or plastic sleeve. The advantage of the paper sleeve and the wooden handle is that the package can be autoclaved to be sterilized (plastic sleeves or handles would melt in the autoclave).